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Amino Acid Biosynthesis Pathways in Diatoms
Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam 14476, Germany
Received: 14 January 2013; in revised form: 4 April 2013 / Accepted: 8 April 2013 / Published: 18 April 2013
Abstract: Amino acids are not only building blocks for proteins but serve as precursors for the synthesis of many metabolites with multiple functions in growth and other biological processes of a living organism. The biosynthesis of amino acids is tightly connected with central carbon, nitrogen and sulfur metabolism. Recent publication of genome sequences for two diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum created an opportunity for extensive studies on the structure of these metabolic pathways. Based on sequence homology found in the analyzed diatomal genes, the biosynthesis of amino acids in diatoms seems to be similar to higher plants. However, one of the most striking differences between the pathways in plants and in diatomas is that the latter possess and utilize the urea cycle. It serves as an important anaplerotic pathway for carbon fixation into amino acids and other N-containing compounds, which are essential for diatom growth and contribute to their high productivity.
Keywords: diatoms; amino acids biosynthesis
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Cite This Article
MDPI and ACS Style
Bromke, M.A. Amino Acid Biosynthesis Pathways in Diatoms. Metabolites 2013, 3, 294-311.
Bromke MA. Amino Acid Biosynthesis Pathways in Diatoms. Metabolites. 2013; 3(2):294-311.
Bromke, Mariusz A. 2013. "Amino Acid Biosynthesis Pathways in Diatoms." Metabolites 3, no. 2: 294-311.