Synthesis and Characterization of Compounds Related to Lisinopril
AbstractLisinopril is a drug of the angiotensin-converting enzyme (ACE) inhibitor class that is primarily used in the treatment of hypertension. During the scale-up of the lisinopril process, one unknown impurity was observed and is identified. The present work describes the origin, synthesis, characterization, and control of this impurity. This paper also describes the synthesis and characterization of three other impurities listed in the European Pharmacopoeia 8.4 (Impurity C, D, and F).
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RAGHAVA REDDY, A.V.; GARAGA, S.; TAKSHINAMOORTHY, C.; NAIDU, A.; DANDALA, R. Synthesis and Characterization of Compounds Related to Lisinopril. Sci. Pharm. 2016, 84, 269-278.
RAGHAVA REDDY AV, GARAGA S, TAKSHINAMOORTHY C, NAIDU A, DANDALA R. Synthesis and Characterization of Compounds Related to Lisinopril. Scientia Pharmaceutica. 2016; 84(2):269-278.Chicago/Turabian Style
RAGHAVA REDDY, Ambati V.; GARAGA, Srinivas; TAKSHINAMOORTHY, Chandiran; NAIDU, Andra; DANDALA, Ramesh. 2016. "Synthesis and Characterization of Compounds Related to Lisinopril." Sci. Pharm. 84, no. 2: 269-278.