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Volume 83
Issue 1
10.3797/scipharm.1409-12
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Article

Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities

by
Niels GULDBRANDSEN
1,
Maria DE MIERI
1,
Mahabir GUPTA
2,
Eleni LIAKOU
3,
Harris PRATSINIS
3,
Dimitris KLETSAS
3,
Eliza CHAITA
4,5,
Nektarios ALIGIANNIS
5,
Alexios-Leandros SKALTSOUNIS
5 and
Matthias HAMBURGER
1,*
1
Division of Pharmaceutical Biology, University of Basel, Klingelbergstrasse 40, CH-4056 Basel, Switzerland
2
CIFLORPAN, College of Pharmacy, University of Panama, Apartado 0824-00172, Panama, Republic of Panama
3
Laboratory of Cell Proliferation & Ageing, Institute of Biosciences & Applications, NCSR “Demokritos”, 15310, Athens, Greece
4
Korres S.A. Natural Products, 57th Athens-Lamia National Road, 32011, Inofyta, Greece
5
Department of Pharmacognosy & Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Zografou, 15771, Greece
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2015, 83(1), 177-190; https://doi.org/10.3797/scipharm.1409-12
Submission received: 21 September 2014 / Accepted: 15 October 2014 / Published: 15 October 2014
Versions Notes

Abstract

A library of 600 taxonomically diverse Panamanian plant extracts was screened for DPPH scavenging and UV-B protective activities, and the methanolic extracts of Mosquitoxylum jamaicense, Combretum cacoucia, and Casearia commersionia were submitted to HPLC-based activity profiling. The compounds located in the active time windows were isolated and identified as gallic acid derivatives and flavonoids. Gallic acid methyl ester (3) and digallic acid derivatives (2, 6) showed the highest DPPH scavenging activity (<10 μg/mL), while protocatechuic acid (7) and isoquercitrin (10) exhibited the highest UV-B protective properties.
Keywords: Panamanian plant extract; HPLC-based activity profiling; DPPH scavenging; UV-B protection Panamanian plant extract; HPLC-based activity profiling; DPPH scavenging; UV-B protection

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MDPI and ACS Style

GULDBRANDSEN, N.; DE MIERI, M.; GUPTA, M.; LIAKOU, E.; PRATSINIS, H.; KLETSAS, D.; CHAITA, E.; ALIGIANNIS, N.; SKALTSOUNIS, A.-L.; HAMBURGER, M. Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities. Sci. Pharm. 2015, 83, 177-190. https://doi.org/10.3797/scipharm.1409-12

AMA Style

GULDBRANDSEN N, DE MIERI M, GUPTA M, LIAKOU E, PRATSINIS H, KLETSAS D, CHAITA E, ALIGIANNIS N, SKALTSOUNIS A-L, HAMBURGER M. Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities. Scientia Pharmaceutica. 2015; 83(1):177-190. https://doi.org/10.3797/scipharm.1409-12

Chicago/Turabian Style

GULDBRANDSEN, Niels, Maria DE MIERI, Mahabir GUPTA, Eleni LIAKOU, Harris PRATSINIS, Dimitris KLETSAS, Eliza CHAITA, Nektarios ALIGIANNIS, Alexios-Leandros SKALTSOUNIS, and Matthias HAMBURGER. 2015. "Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities" Scientia Pharmaceutica 83, no. 1: 177-190. https://doi.org/10.3797/scipharm.1409-12

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