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Sci. Pharm. 2015, 83(1), 177-190; doi:10.3797/scipharm.1409-12

Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities

1
Division of Pharmaceutical Biology, University of Basel, Klingelbergstrasse 40, CH-4056 Basel, Switzerland
2
CIFLORPAN, College of Pharmacy, University of Panama, Apartado 0824-00172, Panama, Republic of Panama
3
Laboratory of Cell Proliferation & Ageing, Institute of Biosciences & Applications, NCSR “Demokritos”, 15310, Athens, Greece
4
Korres S.A. Natural Products, 57th Athens-Lamia National Road, 32011, Inofyta, Greece
5
Department of Pharmacognosy & Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Zografou, 15771, Greece
*
Author to whom correspondence should be addressed.
Received: 21 September 2014 / Accepted: 15 October 2014 / Published: 15 October 2014
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Abstract

A library of 600 taxonomically diverse Panamanian plant extracts was screened for DPPH scavenging and UV-B protective activities, and the methanolic extracts of Mosquitoxylum jamaicense, Combretum cacoucia, and Casearia commersionia were submitted to HPLC-based activity profiling. The compounds located in the active time windows were isolated and identified as gallic acid derivatives and flavonoids. Gallic acid methyl ester (3) and digallic acid derivatives (2, 6) showed the highest DPPH scavenging activity (<10 μg/mL), while protocatechuic acid (7) and isoquercitrin (10) exhibited the highest UV-B protective properties.
Keywords: Panamanian plant extract; HPLC-based activity profiling; DPPH scavenging; UV-B protection Panamanian plant extract; HPLC-based activity profiling; DPPH scavenging; UV-B protection
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

GULDBRANDSEN, N.; DE MIERI, M.; GUPTA, M.; LIAKOU, E.; PRATSINIS, H.; KLETSAS, D.; CHAITA, E.; ALIGIANNIS, N.; SKALTSOUNIS, A.-L.; HAMBURGER, M. Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities. Sci. Pharm. 2015, 83, 177-190.

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