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Sci. Pharm. 2012, 80(2), 311-316; doi:10.3797/scipharm.1201-02

Rapid Determination of Diclofenac in Pharmaceutical Formulations by Capillary Zone Electrophoresis

Department of Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria
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Received: 2 January 2012 / Accepted: 23 February 2012 / Published: 23 February 2012
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Abstract

Capillary electrophoresis is competitive to HPLC and other chromatographic methods, predominantly when charged analytes have to be separated. The time of analysis can be reduced by the use of very short capillaries applying a high voltage. In most instruments which are commercially available the so-called ‘short end’ of the capillary can be used for separation, leading to very rapid separations. In this contribution we want to demonstrate this approach by using Diclofenac Sodium as an analyte.
Keywords: Capillary Zone Electrophoresis; CZE; Diclofenac Sodium; Pharmaceutical Formulations; CE Capillary Zone Electrophoresis; CZE; Diclofenac Sodium; Pharmaceutical Formulations; CE
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

LACHMANN, B.; KRATZEL, M.; NOE, C.R. Rapid Determination of Diclofenac in Pharmaceutical Formulations by Capillary Zone Electrophoresis. Sci. Pharm. 2012, 80, 311-316.

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