Next Article in Journal
Polyacrylic Acid-Protamine Nanoparticles for Scale-Up Experiments in a Microreactor
Previous Article in Journal
Spray Drying as a Novel Method for Producing Nanoparticles Intended for the Application in DPI's
 
 
Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Conference Report

Protamine Based siRNA-Nanoparticles: Particle Composition Dependant Influences on RNA Interference Efficiency

1
Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, Karl-Franzens-University Graz, Austria
2
Institute of Molecular Biology and Biochemistry, Medical University Graz, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2010, 78(3), 686; https://doi.org/10.3797/scipharm.cespt.8.PNM16
Submission received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010

Abstract

The major limitations for the use of small interfering RNA (siRNA) in vivo and in vitro are the relatively high molecular weight, the negative charge, and the susceptibility to nuclease degradation [1]. [...]

Share and Cite

MDPI and ACS Style

REISCHL, D.; JANTSCHER-KRENN, E.; BERNHART, E.; SATTLER, W.; ZIMMER, A. Protamine Based siRNA-Nanoparticles: Particle Composition Dependant Influences on RNA Interference Efficiency. Sci. Pharm. 2010, 78, 686. https://doi.org/10.3797/scipharm.cespt.8.PNM16

AMA Style

REISCHL D, JANTSCHER-KRENN E, BERNHART E, SATTLER W, ZIMMER A. Protamine Based siRNA-Nanoparticles: Particle Composition Dependant Influences on RNA Interference Efficiency. Scientia Pharmaceutica. 2010; 78(3):686. https://doi.org/10.3797/scipharm.cespt.8.PNM16

Chicago/Turabian Style

REISCHL, D., E. JANTSCHER-KRENN, E. BERNHART, W. SATTLER, and A. ZIMMER. 2010. "Protamine Based siRNA-Nanoparticles: Particle Composition Dependant Influences on RNA Interference Efficiency" Scientia Pharmaceutica 78, no. 3: 686. https://doi.org/10.3797/scipharm.cespt.8.PNM16

Article Metrics

Back to TopTop