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Sci. Pharm. 2009, 77(Posters (PO)), 225; doi:10.3797/scipharm.oephg.21.PO-26 (registering DOI)

Honokiol Modulates GABAA Receptors Subunit Specifically

1
Department of Pharmacology, University of Vienna, Althanstr. 14, 1190 Wien, Österreich
2
Institute of Pharmaceutical Biology, University of Basel, Klingelbergstraße 50, 4056, Basel, Switzerland
3
Department of Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria
*
Author to whom correspondence should be addressed.
Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Honokiol, a neolignan compound isolated from Magnolia species has been suggested to interact with GABAA receptors. Evidence comes from honokiol-induced enhanced [3H]muscimol binding [1] and anxiolytic action in behavioural studies [2]. The molecular mechanism and possible subunit-specific effects of honokiol on GABAA receptors are currently unknown.[...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

BABURIN, I.; TAFERNER, B.; WIESNER, K.; HAMBURGER, M.; SCHÜHLY, W.; HERING, S. Honokiol Modulates GABAA Receptors Subunit Specifically. Sci. Pharm. 2009, 77, 225.

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