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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2009, 77(Posters (PO)), 224; https://doi.org/10.3797/scipharm.oephg.21.PO-25 (registering DOI)

Synthesis of Deuterated Analogs of Honokiol

1
Institute of Pharm. Sciences, Dept. of Pharm. Chemistry, University of Graz, Universitätsplatz 1, 8010 Graz, Austria
2
Institute of Pharm. Sciences, Dept. of Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria
*
Author to whom correspondence should be addressed.
Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Abstract

The genus Magnolia plays a role in American as well as in Asian medicinal systems such as TCM or Japanese Kampo medicine [1, 2]. Main lignan constituents in the seeds of the north american Magnolia grandiflora are honokiol (1) and 4'-O-methyl-honokiol. They are known to possess anti-inflammatory activities with COX-2 inhibitory activity (IC50) of about 0.1 to 3 μM.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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HÜFNER, A.; SCHÜHLY, W. Synthesis of Deuterated Analogs of Honokiol. Sci. Pharm. 2009, 77, 224.

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