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Sci. Pharm. 2009, 77(Posters (PO)), 224; doi:10.3797/scipharm.oephg.21.PO-25 (registering DOI)

Synthesis of Deuterated Analogs of Honokiol

1
Institute of Pharm. Sciences, Dept. of Pharm. Chemistry, University of Graz, Universitätsplatz 1, 8010 Graz, Austria
2
Institute of Pharm. Sciences, Dept. of Pharmacognosy, University of Graz, Universitätsplatz 4, 8010 Graz, Austria
*
Author to whom correspondence should be addressed.
Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Abstract

The genus Magnolia plays a role in American as well as in Asian medicinal systems such as TCM or Japanese Kampo medicine [1, 2]. Main lignan constituents in the seeds of the north american Magnolia grandiflora are honokiol (1) and 4'-O-methyl-honokiol. They are known to possess anti-inflammatory activities with COX-2 inhibitory activity (IC50) of about 0.1 to 3 μM.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

HÜFNER, A.; SCHÜHLY, W. Synthesis of Deuterated Analogs of Honokiol. Sci. Pharm. 2009, 77, 224.

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