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Sci. Pharm. 2009, 77(Posters (PO)), 208; doi:10.3797/scipharm.oephg.21.PO-09 (registering DOI)

Enantioseparation with Capillary Electrophoresis (CE) as Evidence of Chirality Retention during Kolbe Electrolysis of Amino Acids

Department of Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria
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Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Abstract

The radical Kolbe electrolysis can be applied to synthesize non-proteinogenic amino acids starting from ʟ-glutamic acid (or L-aspartic acid, respectively). Using suitable protecting groups for both amino and carboxy functionalities, the retention of chirality at the α-carbon atom can be expected.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

DÖRNER, B.; LACHMANN, B.; KRATZEL, M. Enantioseparation with Capillary Electrophoresis (CE) as Evidence of Chirality Retention during Kolbe Electrolysis of Amino Acids. Sci. Pharm. 2009, 77, 208.

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