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Sci. Pharm. 2009, 77(Short Lectures (SL)), 194; doi:10.3797/scipharm.oephg.21.SL-27 (registering DOI)

Reverse Chemical Proteomics in Drug Discovery

Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW, 2109 Australia
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Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Abstract

With advances in separation technology and structure elucidation, the main bottleneck limiting drug development from natural products is the identification of their cellular targets. Although effective therapeutic agents can be developed and successfully administered without knowledge of the underlying mechanism of action, elucidation of drug target proteins is essential in the design of new compounds with improved safety and efficacy [1].[...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

GOTSBACHER, M.; KARUSO, P. Reverse Chemical Proteomics in Drug Discovery. Sci. Pharm. 2009, 77, 194.

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