Reverse Chemical Proteomics in Drug Discovery
AbstractWith advances in separation technology and structure elucidation, the main bottleneck limiting drug development from natural products is the identification of their cellular targets. Although effective therapeutic agents can be developed and successfully administered without knowledge of the underlying mechanism of action, elucidation of drug target proteins is essential in the design of new compounds with improved safety and efficacy .[...]
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GOTSBACHER, M.; KARUSO, P. Reverse Chemical Proteomics in Drug Discovery. Sci. Pharm. 2009, 77, 194.
GOTSBACHER M, KARUSO P. Reverse Chemical Proteomics in Drug Discovery. Scientia Pharmaceutica. 2009; 77(Short Lectures (SL)):194.Chicago/Turabian Style
GOTSBACHER, M.; KARUSO, P. 2009. "Reverse Chemical Proteomics in Drug Discovery." Sci. Pharm. 77, Short Lectures (SL): 194.