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Sci. Pharm. 2007, 75(3), 97-110; doi:10.3797/scipharm.2007.75.97 (registering DOI)

In Vitro Release Studies on Multiple and Simple Emulsions of α-Tocopherol with Pistacia Leaves

1
Department of Pharmaceutical Technology, Faculty of Pharmacy, Ege University, 35100-Bornova-İzmir-Turkey
2
Department of Pharmacognosy, Faculty of Pharmacy, Ege University, 35100- Bornova- İzmir-Turkey
*
Author to whom correspondence should be addressed.
Received: 28 November 2006 / Accepted: 9 September 2007 / Published: 28 September 2007
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Abstract

α-Tocopherol is the most effective lipid soluble natural antioxidant and free-radical scavenger. The present study aimed to evaluate the performance of the extracts of Pistacia lentiscus, P. lentiscus var. chia and P. terebinthus leaves as additives on in vitro release of α-tocopherol. The α-tocopherol content of Pistacia extracts were determined and the release was investigated from w/o/w multiple emulsion, w/o and o/w simple emulsions through cellulose acetate and cellulose nitrate membranes by using HPLC-UV method. As significant increase in the extent of α-tocopherol release was observed with the addition of Pistacia extracts in all emulsions. They could be suggested as suitable additives in α-tocopherol containing formulations.
Keywords: α-tocopherol; emulsions; Pistacia lentiscus L.; Pistacia lentiscus var.chia; Pistacia terebinthus α-tocopherol; emulsions; Pistacia lentiscus L.; Pistacia lentiscus var.chia; Pistacia terebinthus
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Özer, Ö.; Kıvçak, B.; Mutlu, B.; Akay, S.; Sağlam, H.; Tömek, S. In Vitro Release Studies on Multiple and Simple Emulsions of α-Tocopherol with Pistacia Leaves. Sci. Pharm. 2007, 75, 97-110.

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