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Sci. Pharm.
Volume 75
Issue 2
10.3797/scipharm.2007.75.81
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Article

Study of Local Anaesthetics. Part 172* Comparison of the Influence of Auxilliary Substances on Physicochemical Parameters of Two Phenylcarbamic Acid Derivatives

by
Klára Gardavská
1,*,
Jozef Čižmárik
2 and
Marián Žabka
1
1
Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University, Odbojárov 10, 832 32 Bratislava, Slovak Republic
2
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Odbojárov 10, 832 32 Bratislava, Slovak Republic
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2007, 75(2), 81-96; https://doi.org/10.3797/scipharm.2007.75.81
Submission received: 16 February 2007 / Accepted: 9 March 2007 / Published: 29 June 2007
Versions Notes

Abstract

It this work was studied the influence of polyols (propylene glycol, glycerol and sorbitol) on the physicochemical parameters (partition coefficient and surface tension) and liberation from aqueous solutions with propylene glycol of two derivatives of phenylcarbamic acid. Studied parameters and liberation were influenced by the structure of the studied derivatives and with the type and concentration of polyols.
Keywords: artition coefficient; surface tension; derivative of phenylcarbamic acids; in vitro liberation artition coefficient; surface tension; derivative of phenylcarbamic acids; in vitro liberation

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MDPI and ACS Style

Gardavská, K.; Čižmárik, J.; Žabka, M. Study of Local Anaesthetics. Part 172* Comparison of the Influence of Auxilliary Substances on Physicochemical Parameters of Two Phenylcarbamic Acid Derivatives. Sci. Pharm. 2007, 75, 81-96. https://doi.org/10.3797/scipharm.2007.75.81

AMA Style

Gardavská K, Čižmárik J, Žabka M. Study of Local Anaesthetics. Part 172* Comparison of the Influence of Auxilliary Substances on Physicochemical Parameters of Two Phenylcarbamic Acid Derivatives. Scientia Pharmaceutica. 2007; 75(2):81-96. https://doi.org/10.3797/scipharm.2007.75.81

Chicago/Turabian Style

Gardavská, Klára, Jozef Čižmárik, and Marián Žabka. 2007. "Study of Local Anaesthetics. Part 172* Comparison of the Influence of Auxilliary Substances on Physicochemical Parameters of Two Phenylcarbamic Acid Derivatives" Scientia Pharmaceutica 75, no. 2: 81-96. https://doi.org/10.3797/scipharm.2007.75.81

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