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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2007, 75(1), 35-54; https://doi.org/10.3797/scipharm.2007.75.35 (registering DOI)

Antioxidant and Antimicrobial Activities of Hyptis suaveolens Essential Oil

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200, Thailand
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Author to whom correspondence should be addressed.
Received: 1 January 2007 / Accepted: 1 January 2007 / Published: 30 March 2007
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Abstract

The essential oil of Hyptis suaveolens obtained by steam distillation was examined for its antioxidant and antimicrobial activities. The antioxidant activity was determined by means of the DPPH radical scavenging test and ABTS free radical decolorization assay. Results from both methods indicate that the antioxidant activity of H. suaveolens oil is time and concentration dependent. The antioxidant potential of H. suaveolens oil determined by the DPPH method expressed as IC50 was 3.72 mg/ml whereas the TEAC value determined by the ABTS assay was 65.02 µM/mg. The antimicrobial activity of the essential oil was assessed by the dilution and well diffusion methods. The results show that the antifungal potential of H. suaveolens oil is more pronounced than its antibacterial properties. Its fungal growth inhibitory activity was dose dependent with a MID value of 1:640. The 20% ethanolic solution of H. suaveolens oil had antifungal power similar to 6% boric acid, 2% benzoic acid, or 5% salicylic acid but higher than 4% phenol. The activity decreased when the oil was stored at high temperature (> 40°C). The results of GC-MS analysis indicated the changes in oil composition which led to the decrease in antifungal activity.
Keywords: Essential oil; Antioxidant; ABTS; DPPH; Antimicrobial; Hyptis suaveolens Essential oil; Antioxidant; ABTS; DPPH; Antimicrobial; Hyptis suaveolens
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Nantitanon, W.; Chowwanapoonpohn, S.; Okonogi, S. Antioxidant and Antimicrobial Activities of Hyptis suaveolens Essential Oil. Sci. Pharm. 2007, 75, 35-54.

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