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Diseases 2018, 6(1), 3; doi:10.3390/diseases6010003

Hepatitis B Virus Genotype C is Predominant in Myanmar

Department of Molecular Virology, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8677, Japan
Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-ku, Tokyo 173-8610, Japan
Author to whom correspondence should be addressed.
Received: 6 December 2017 / Revised: 23 December 2017 / Accepted: 25 December 2017 / Published: 26 December 2017
(This article belongs to the Special Issue Hepatitis and Treatment)
View Full-Text   |   Download PDF [190 KB, uploaded 26 December 2017]


Myanmar is adjacent to India, Bangladesh, Thailand, Laos and China. In Myanmar, the prevalence of hepatitis B virus (HBV) infections is 6.5% and accounts for 60% of hepatocellular carcinoma. HBV has nine genotypes that have been identified by molecular genetic analysis. HBV genotypes are associated with several clinical features. We reviewed the prevalence of HBV genotypes in Myanmar and neighboring countries. We also reviewed HBV genotypes in refugees from Myanmar. HBV subgenotype C1 is predominant in Myanmar. As HBV genotype C is associated with hepatocellular carcinoma (HCC), it is important to screen for cirrhosis and HCC and to prevent their development in HBV-infected individuals of Myanmar. View Full-Text
Keywords: HBV genotypes; hepatitis B virus; Myanmar HBV genotypes; hepatitis B virus; Myanmar
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Nwe Win, N.; Nakamoto, S.; Myint Sein, M.; Moriyama, M.; Kanda, T.; Shirasawa, H. Hepatitis B Virus Genotype C is Predominant in Myanmar. Diseases 2018, 6, 3.

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