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Diseases 2015, 3(2), 111-121; doi:10.3390/diseases3020111

Auxo-Endocrinological Approach to Celiac Children

1
Internal Medicine and Therapeutics Department, Pediatrics and Adolescentology Unit, University of Pavia, Fondazione IRCCS San Matteo, Viale Golgi 19, 27100 Pavia, Italy
2
Internal Medicine and Therapeutics Department, Pediatrics and Adolescentology Unit, University of Pavia, Fondazione IRCCS San Matteo, Viale Golgi 19, 27100 Pavia, Italy
3
Department of Pediatrics, Pediatric and Infectious Diseases Unit, Bambino Gesù Children Hospital, IRCCS, Piazza Sant'Onofrio 4, 00165 Rome, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Stefano Guandalini and Sonia Kupfer
Received: 23 April 2015 / Revised: 29 May 2015 / Accepted: 1 June 2015 / Published: 19 June 2015
(This article belongs to the Special Issue Celiac Disease)
View Full-Text   |   Download PDF [939 KB, uploaded 19 June 2015]   |  

Abstract

Celiac disease is a permanent genetically determined intolerance to gluten that generally presents with gastrointestinal symptoms in young children and extraintestinal manifestations (endocrinological, dermatological, neurological, etc.) later. Furthermore, many studies demonstrate the close association between celiac and endocrine diseases, including growth and pubertal disorders, type I diabetes mellitus and autoimmune thyroid diseases, probably due to the presence of a common genetic predisposition. Follow-up for celiac children after the start of gluten-free diet is mandatory to avoid complications such as growth hormone deficiency. The present review deals with the problem of the diagnosis of endocrine-associated diseases in celiac children and gives suggestions for correct management and follow-up of these patients. View Full-Text
Keywords: celiac disease; children; endocrine diseases; linear growth celiac disease; children; endocrine diseases; linear growth
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MDPI and ACS Style

Bozzola, M.; Meazza, C.; Villani, A. Auxo-Endocrinological Approach to Celiac Children. Diseases 2015, 3, 111-121.

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