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Open AccessCommunication
Cosmetics 2017, 4(1), 9; doi:10.3390/cosmetics4010009

A Validated HPLC Method for the Determination of Vanillyl Butyl Ether in Cosmetic Preparations

Suavizantes y plastificantes Bituminosos S.L. Polígono Industrial de Cheste, vial 6, 46380 Cheste, Valencia, Spain
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Academic Editor: Enzo Berardesca
Received: 24 October 2016 / Revised: 26 January 2017 / Accepted: 4 February 2017 / Published: 10 February 2017
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Abstract

A specific HPLC (High-Performance Liquid Chromatography) method has been developed and validated for the determination of vanillyl butyl ether in cosmetic products. The extraction procedure with an isopropanol water 1:1 mixture is described. The method uses a RP-C-18 column with isocratic elution and an ultraviolet (UV) detector. The mobile phase consists of a mixture of acetonitrile and buffer (Na2HPO4 20 mM in water) (30:70 v/v) with a variable flow rate. The method was validated with respect to accuracy, precision (repeatability and reproducibility), specificity and linearity. The procedure described here is simple, selective and reliable for routine quality control analysis and stability tests of commercially available cosmetic products. View Full-Text
Keywords: vanillyl butyl ether; HPLC; method validation; cosmetic product vanillyl butyl ether; HPLC; method validation; cosmetic product
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Ríos, F.; Alberola, A.; Melendez, J.; Muedra, G.; Trigo, F. A Validated HPLC Method for the Determination of Vanillyl Butyl Ether in Cosmetic Preparations. Cosmetics 2017, 4, 9.

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