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Cosmetics 2017, 4(1), 4; doi:10.3390/cosmetics4010004

Oxidative Stress and Ageing: The Influence of Environmental Pollution, Sunlight and Diet on Skin

Dermatological Sciences, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle Upon Tyne NE2 4HH, UK
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Author to whom correspondence should be addressed.
Academic Editor: Johanna Maria Gillbro
Received: 25 November 2016 / Revised: 21 December 2016 / Accepted: 3 January 2017 / Published: 10 January 2017
View Full-Text   |   Download PDF [192 KB, uploaded 10 January 2017]

Abstract

Skin ageing is a complex process that is determined by both intrinsic and extrinsic factors, which leads to a progressive loss of structure and function. There is extensive evidence indicating that oxidative stress induced by reactive oxygen species plays an important role in the process of human skin ageing. Mitochondria are the major source of cellular oxidative stress and are widely implicated in cutaneous ageing. Extrinsic skin ageing is driven to a large extent by environmental factors and external stressors such as ultraviolet radiation (UVR), pollution and lifestyle factors which have been shown to stimulate the production of reactive oxygen species and generate oxidative stress. The oxidative damage from these exogenous sources can impair skin structure and function, leading to the phenotypic features of extrinsic skin ageing. The following review highlights the current evidence surrounding the role of mitochondria and oxidative stress in the ageing process and the influence of environmental factors such as ultraviolet radiation, pollution and diet on skin ageing. View Full-Text
Keywords: skin ageing; reactive oxygen species; ROS; oxidative stress; pollution; UVR; sunlight; diet skin ageing; reactive oxygen species; ROS; oxidative stress; pollution; UVR; sunlight; diet
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Naidoo, K.; Birch-Machin, M.A. Oxidative Stress and Ageing: The Influence of Environmental Pollution, Sunlight and Diet on Skin. Cosmetics 2017, 4, 4.

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