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Biology 2015, 4(1), 151-160; doi:10.3390/biology4010151

Oncostatin M Modulation of Lipid Storage

1
Adipocyte Biology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
2
Department of Biological Sciences, Louisiana State University, 202 Life Sciences Building, Baton Rouge, LA 70803, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Annette Graham
Received: 21 November 2014 / Revised: 29 January 2015 / Accepted: 11 February 2015 / Published: 13 February 2015
(This article belongs to the Special Issue Lipid Metabolism)
View Full-Text   |   Download PDF [259 KB, uploaded 13 February 2015]   |  

Abstract

Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism. View Full-Text
Keywords: oncostatin M; gp130 cytokines; adipocyte; obesity; adipose tissue oncostatin M; gp130 cytokines; adipocyte; obesity; adipose tissue
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Elks, C.M.; Stephens, J.M. Oncostatin M Modulation of Lipid Storage. Biology 2015, 4, 151-160.

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