Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions

doi:10.3390/antibiotics1010017

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Antibiotics 2012, 1(1), 17-24; doi:10.3390/antibiotics1010017

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Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions

Erkki Kolehmainen* , Hannu Salo and Jukka Korpela

Department of Chemistry, University of Jyväskylä, P.O. Box 35, FIN-40014 Jyväskylä, Finland

* Author to whom correspondence should be addressed.

Received: 30 July 2012; in revised form: 23 August 2012 / Accepted: 10 September 2012 / Published: 19 September 2012

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Abstract: It was shown that 5-chloro-8-hydroxyquinoline, an antituberculosis agent, gels aqueous alcohol solutions efficiently. Thermal stability and gel-to-sol transition temperature of 1% gel in CD₃OD/D₂O (2:1) was studied by ¹H-NMR. Fibrous structures of four xerogels have been characterized by scanning electron microscope.

Keywords: gel; 5-chloro-8-hydroxyquinoline; Mycobacterium tuberculosis

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MDPI and ACS Style

Kolehmainen, E.; Salo, H.; Korpela, J. Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions. Antibiotics 2012, 1, 17-24.

AMA Style

Kolehmainen E, Salo H, Korpela J. Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions. Antibiotics. 2012; 1(1):17-24.

Chicago/Turabian Style

Kolehmainen, Erkki; Salo, Hannu; Korpela, Jukka. 2012. "Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions." Antibiotics 1, no. 1: 17-24.

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