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Biosensors 2018, 8(3), 61; https://doi.org/10.3390/bios8030061

Application of Biosensors Based on Lipid Membranes for the Rapid Detection of Toxins

1
Laboratory of Inorganic & Analytical Chemistry, School of Chemical Engineering, Department 1, Chemical Sciences, National Technical University of Athens, 9 Iroon Polytechniou St., 15780 Athens, Greece
2
Laboratory of Environmental Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis-Kouponia, 15771 Athens, Greece
3
Laboratory of Simulation of Industrial Processes, Department of Industrial Management and Technology, School of Maritime and Industry, University of Piraeus, 18534 Pireus, Greece
*
Author to whom correspondence should be addressed.
Received: 17 April 2018 / Revised: 4 June 2018 / Accepted: 21 June 2018 / Published: 26 June 2018
(This article belongs to the Special Issue Biosensors for Environmental Applications)
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Abstract

Lipid assemblies in the form of two dimensional films have been used extensively as biosensing platforms. These films exhibit certain similarities with cell membranes, thus providing a suitable means for the immobilization of proteinaceous moieties and, further, a number of intrinsic signal amplification mechanisms. Their implementation in the detection of toxins yielded reliable and fast detectors for in field analyses of environmental and clinical samples. Some examples are presented herein, including aflatoxin and cholera toxin detection. The conditions and parameters that determine the analytical specifications of the lipid membrane sensors are discussed, advantages and technology bottlenecks are reviewed, and possible further developments are highlighted. View Full-Text
Keywords: biosensors; lipid membranes; toxins biosensors; lipid membranes; toxins
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Nikoleli, G.-P.; Nikolelis, D.P.; Siontorou, C.G.; Karapetis, S.; Nikolelis, M.-T. Application of Biosensors Based on Lipid Membranes for the Rapid Detection of Toxins. Biosensors 2018, 8, 61.

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