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Biosensors 2018, 8(2), 54; https://doi.org/10.3390/bios8020054

Aptamer-Based Biosensors for Antibiotic Detection: A Review

Institute of Electronic and Sensory Materials, Faculty of Materials Science and Materials Technology, Technological University Freiberg, Akademie Str. 6, 09599 Freiberg, Germany
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Received: 26 April 2018 / Revised: 4 June 2018 / Accepted: 5 June 2018 / Published: 11 June 2018
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Abstract

Antibiotic resistance and, accordingly, their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develop robust, easy, and sensitive methods for rapid evaluation of antibiotics and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recently-developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics, like β-lactams, aminoglycosides, anthracyclines, chloramphenicol, (fluoro)quinolones, lincosamide, tetracyclines, and sulfonamides are presented in this paper. View Full-Text
Keywords: biosensor; aptasensor; aptamer; antibiotic; ampicillin; penicillin; gentamicin; kanamycin; neomycin; tobramycin; streptomycin; daunomycin; chloramphenicol; ciprofloxacin; danofloxacin; enrofloxacin; ofloxacin; lincomycin; oxytetracycline; tetracycline; sulfadimethoxine biosensor; aptasensor; aptamer; antibiotic; ampicillin; penicillin; gentamicin; kanamycin; neomycin; tobramycin; streptomycin; daunomycin; chloramphenicol; ciprofloxacin; danofloxacin; enrofloxacin; ofloxacin; lincomycin; oxytetracycline; tetracycline; sulfadimethoxine
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Mehlhorn, A.; Rahimi, P.; Joseph, Y. Aptamer-Based Biosensors for Antibiotic Detection: A Review. Biosensors 2018, 8, 54.

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