Next Article in Journal
T1-MRI Fluorescent Iron Oxide Nanoparticles by Microwave Assisted Synthesis
Next Article in Special Issue
Magnetic Nanoparticles Cross the Blood-Brain Barrier: When Physics Rises to a Challenge
Previous Article in Journal
Structural Stability of Diffusion Barriers in Cu/Ru/MgO/Ta/Si
Previous Article in Special Issue
Iron Oxide Nanoparticles Coated with a Phosphorothioate Oligonucleotide and a Cationic Peptide: Exploring Four Different Ways of Surface Functionalization
Article Menu

Export Article

Open AccessReview
Nanomaterials 2015, 5(4), 1853-1879;

Gold Nanotheranostics: Proof-of-Concept or Clinical Tool?

UCIBIO, Department of Life Sciences, Faculdade de Ciências e Tecnologia, Campus Caparica, 2829-516 Caparica, Portugal
Author to whom correspondence should be addressed.
Academic Editor: Subramanian Tamil Selvan
Received: 22 August 2015 / Revised: 4 October 2015 / Accepted: 27 October 2015 / Published: 3 November 2015
(This article belongs to the Special Issue Nanoparticles in Theranostics)
View Full-Text   |   Download PDF [704 KB, uploaded 3 November 2015]   |  


Nanoparticles have been making their way in biomedical applications and personalized medicine, allowing for the coupling of diagnostics and therapeutics into a single nanomaterial—nanotheranostics. Gold nanoparticles, in particular, have unique features that make them excellent nanomaterials for theranostics, enabling the integration of targeting, imaging and therapeutics in a single platform, with proven applicability in the management of heterogeneous diseases, such as cancer. In this review, we focus on gold nanoparticle-based theranostics at the lab bench, through pre-clinical and clinical stages. With few products facing clinical trials, much remains to be done to effectively assess the real benefits of nanotheranostics at the clinical level. Hence, we also discuss the efforts currently being made to translate nanotheranostics into the market, as well as their commercial impact. View Full-Text
Keywords: nanotheranostics; diagnostics; targeted therapy; cancer; gold nanoparticles; precision medicine; theranostics nanotheranostics; diagnostics; targeted therapy; cancer; gold nanoparticles; precision medicine; theranostics

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Pedrosa, P.; Vinhas, R.; Fernandes, A.; Baptista, P.V. Gold Nanotheranostics: Proof-of-Concept or Clinical Tool? Nanomaterials 2015, 5, 1853-1879.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Nanomaterials EISSN 2079-4991 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top