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Nanomaterials 2015, 5(4), 1690-1703; doi:10.3390/nano5041690

Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy

The Pharmaceutical Research Institute, 1 Discovery Drive, Rensselaer, NY 12144, USA
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Academic Editor: Thomas Nann
Received: 20 August 2015 / Revised: 23 September 2015 / Accepted: 1 October 2015 / Published: 14 October 2015
(This article belongs to the Special Issue Nanoparticles Assisted Drug Delivery)
View Full-Text   |   Download PDF [730 KB, uploaded 14 October 2015]   |  

Abstract

The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and treatment moieties on the surface and in the core, resulting in targeted delivery of the imaging or treatment modalities, specifically to the tumor. Multifunctional nanoparticles also enable simultaneous delivery of multiple treatment agents, resulting in effective combinatorial therapeutic regimens against cancer. In this review, various multifunctional nanoparticle systems that feature a variety of targeting moieties for in vitro and/or in vivo cancer imaging and therapy are discussed. View Full-Text
Keywords: cancer therapy; drug delivery; multifunctional nanoparticles; nanotechnology; tumor targeting; imaging cancer therapy; drug delivery; multifunctional nanoparticles; nanotechnology; tumor targeting; imaging
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Srinivasan, M.; Rajabi, M.; Mousa, S.A. Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy. Nanomaterials 2015, 5, 1690-1703.

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