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J. Funct. Biomater. 2012, 3(3), 528-543; doi:10.3390/jfb3030528
Review

Surface Treatment of Polymeric Materials Controlling the Adhesion of Biomolecules

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Received: 21 May 2012; in revised form: 25 July 2012 / Accepted: 26 July 2012 / Published: 7 August 2012
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Abstract: This review describes different strategies of surface elaboration for a better control of biomolecule adsorption. After a brief description of the fundamental interactions between surfaces and biomolecules, various routes of surface elaboration are presented dealing with the attachment of functional groups mostly thanks to plasma techniques, with the grafting to and from methods, and with the adsorption of surfactants. The grafting of stimuli-responsive polymers is also pointed out. Then, the discussion is focused on the protein adsorption phenomena showing how their interactions with solid surfaces are complex. The adsorption mechanism is proved to be dependent on the solid surface physicochemical properties as well as on the surface and conformation properties of the proteins. Different behaviors are also reported for complex multiple protein solutions.
Keywords: surface; polymer; modification; bioadhesion; biomolecules surface; polymer; modification; bioadhesion; biomolecules
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Poncin-Epaillard, F.; Vrlinic, T.; Debarnot, D.; Mozetic, M.; Coudreuse, A.; Legeay, G.; El Moualij, B.; Zorzi, W. Surface Treatment of Polymeric Materials Controlling the Adhesion of Biomolecules. J. Funct. Biomater. 2012, 3, 528-543.

AMA Style

Poncin-Epaillard F, Vrlinic T, Debarnot D, Mozetic M, Coudreuse A, Legeay G, El Moualij B, Zorzi W. Surface Treatment of Polymeric Materials Controlling the Adhesion of Biomolecules. Journal of Functional Biomaterials. 2012; 3(3):528-543.

Chicago/Turabian Style

Poncin-Epaillard, Fabienne; Vrlinic, Tjasa; Debarnot, Dominique; Mozetic, Miran; Coudreuse, Arnaud; Legeay, Gilbert; El Moualij, Benaïssa; Zorzi, Willy. 2012. "Surface Treatment of Polymeric Materials Controlling the Adhesion of Biomolecules." J. Funct. Biomater. 3, no. 3: 528-543.



J. Funct. Biomater. EISSN 2079-4983 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert