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Computation 2016, 4(1), 7; doi:10.3390/computation4010007

Applications of Computational Modelling and Simulation of Porous Medium in Tissue Engineering

School of Chemical Engineering, Oklahoma State University, 212 Cordell North Stillwater, OK 74078, USA
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Academic Editors: Qinjun Kang and Li Chen
Received: 1 December 2015 / Accepted: 29 January 2016 / Published: 6 February 2016
(This article belongs to the Special Issue Advances in Modeling Flow and Transport in Porous Media)
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Abstract

In tissue engineering, porous biodegradable scaffolds are used as templates for regenerating required tissues. With the advances in computational tools, many modeling approaches have been considered. For example, fluid flow through porous medium can be modeled using the Brinkman equation where permeability of the porous medium has to be defined. In this review, we summarize various models recently reported for defining permeability and non-invasive pressure drop monitoring as a tool to validate dynamic changes in permeability. We also summarize some models used for scaffold degradation and integrating mass transport in the simulation. View Full-Text
Keywords: simulation; mathematical modelling; tissue engineering simulation; mathematical modelling; tissue engineering
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

German, C.L.; Madihally, S.V. Applications of Computational Modelling and Simulation of Porous Medium in Tissue Engineering. Computation 2016, 4, 7.

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