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J. Clin. Med. 2017, 6(9), 89; doi:10.3390/jcm6090089

Process and Pitfalls of Sperm Cryopreservation

Section of Investigative Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
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Academic Editor: Lindsay Brown
Received: 1 August 2017 / Revised: 31 August 2017 / Accepted: 12 September 2017 / Published: 19 September 2017
View Full-Text   |   Download PDF [232 KB, uploaded 19 September 2017]

Abstract

Sperm cryopreservation has been utilized routinely for over 40 years to preserve fertility in men undergoing cancer therapy and allow conception for infertile couples. This article provides a concise and up-to-date review of the literature and covers the latest advances in sperm cryopreservation and its array of clinical indications. Over recent years, the scope of clinical indications used for sperm cryopreservation has expanded widely. Consequently, more patient groups are eligible for sperm freezing, requiring specialist resources and higher running costs. Although sperm cryopreservation prior to cancer therapy is readily available in many countries, referral rates by oncology specialists and levels of patient engagement with cryopreservation services are both reported as low. Furthermore, sperm banking continues to raise ethical issues such whether sperm donation should be anonymous and whether sperm can be utilized posthumously by the surviving partner without consent from the patient. This review focuses on the technological advances and ethical controversies in sperm cryopreservation, and how better understanding of these issues could lead to improved access to fertility preserving treatment for patients. View Full-Text
Keywords: cancer; fertility; sperm; cryopreservation; ethics cancer; fertility; sperm; cryopreservation; ethics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Rozati, H.; Handley, T.; Jayasena, C. Process and Pitfalls of Sperm Cryopreservation. J. Clin. Med. 2017, 6, 89.

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