Table of Contents
J. Clin. Med., Volume 6, Issue 2 (February 2017)
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Cover Story The review presented by Cervantes Gracia and colleagues discusses the most prominent molecules that [...] Read more. The review presented by Cervantes Gracia and colleagues discusses the most prominent molecules that play an important role in cardiovascular disease (CVD) pathophysiology, gives an emphasis on the different sources and types of reactive oxygen species (ROS) in CVD and highlights the relationship between CVD and oxidative stress. Though currently a clear aetiology of CVD has not been established, the involvement of ROS has gained great interest. In CVD, it has become evident that ROS links and modulates numerous cellular metabolic cascades that underlie its genesis. Nevertheless a better understanding how ROS contribute to CVD pathophysiology is clearly needed and new approaches might be necessary to accomplish this aim. View the paper here.