Viral Oncology: Molecular Biology and Pathogenesis
AbstractOncoviruses are implicated in approximately 12% of all human cancers. A large number of the world’s population harbors at least one of these oncoviruses, but only a small proportion of these individuals go on to develop cancer. The interplay between host and viral factors is a complex process that works together to create a microenvironment conducive to oncogenesis. In this review, the molecular biology and oncogenic pathways of established human oncoviruses will be discussed. Currently, there are seven recognized human oncoviruses, which include Epstein-Barr Virus (EBV), Human Papillomavirus (HPV), Hepatitis B and C viruses (HBV and HCV), Human T-cell lymphotropic virus-1 (HTLV-1), Human Herpesvirus-8 (HHV-8), and Merkel Cell Polyomavirus (MCPyV). Available and emerging therapies for these oncoviruses will be mentioned. View Full-Text
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Mui, U.N.; Haley, C.T.; Tyring, S.K. Viral Oncology: Molecular Biology and Pathogenesis. J. Clin. Med. 2017, 6, 111.
Mui UN, Haley CT, Tyring SK. Viral Oncology: Molecular Biology and Pathogenesis. Journal of Clinical Medicine. 2017; 6(12):111.Chicago/Turabian Style
Mui, Uyen N.; Haley, Christopher T.; Tyring, Stephen K. 2017. "Viral Oncology: Molecular Biology and Pathogenesis." J. Clin. Med. 6, no. 12: 111.