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J. Clin. Med. 2016, 5(10), 91; doi:10.3390/jcm5100091

Advances in Radiotherapy Management of Esophageal Cancer

1
Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA
2
Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Jane Grant-Kels
Received: 18 July 2016 / Revised: 30 September 2016 / Accepted: 17 October 2016 / Published: 21 October 2016
(This article belongs to the Special Issue Updates on Treatment of Esophageal Cancer)
View Full-Text   |   Download PDF [210 KB, uploaded 21 October 2016]

Abstract

Radiation therapy (RT) as part of multidisciplinary oncologic care has been marked by profound advancements over the past decades. As part of multimodality therapy for esophageal cancer (EC), a prime goal of RT is to minimize not only treatment toxicities, but also postoperative complications and hospitalizations. Herein, discussion commences with the historical approaches to treating EC, including seminal trials supporting multimodality therapy. Subsequently, the impact of RT techniques, including three-dimensional conformal RT, intensity-modulated RT, and proton beam therapy, is examined through available data. We further discuss existing data and the potential for further development in the future, with an appraisal of the future outlook of technological advancements of RT for EC. View Full-Text
Keywords: esophageal cancer; three-dimensional conformal radiation therapy; intensity-modulated radiation therapy; proton beam therapy; trimodality therapy esophageal cancer; three-dimensional conformal radiation therapy; intensity-modulated radiation therapy; proton beam therapy; trimodality therapy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Verma, V.; Moreno, A.C.; Lin, S.H. Advances in Radiotherapy Management of Esophageal Cancer. J. Clin. Med. 2016, 5, 91.

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