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J. Clin. Med. 2015, 4(5), 965-969; doi:10.3390/jcm4050965

Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism

1
Division of Endocrinology and Diabetes, RWTH Aachen University, 52062 Aachen, Germany
2
Department of Neuroradiology, RWTH Aachen University, 52062 Aachen, Germany
3
Department of Neurosurgery, University Hospital Essen, 45147 Essen, Germany
*
Author to whom correspondence should be addressed.
Academic Editors: Günter Stalla and Anna Kopczak
Received: 27 March 2015 / Revised: 30 April 2015 / Accepted: 6 May 2015 / Published: 15 May 2015
(This article belongs to the Special Issue Neuroendocrine Disturbances after Brain Damage)
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Abstract

We report a case of a previously undiagnosed panhypopituitarism initially presenting as a full-blown Addisonian crisis with hypoglycemia, hyponatremia, hypotension and neuropsychological symptoms, more than 30 years after a severe traumatic brain injury (TBI). The patient also displayed clearly visible pathognomonic clinical signs of long-standing pituitary dysfunction. The case highlights the importance of being aware of endocrine sequelae even decades after serious TBI. View Full-Text
Keywords: traumatic brain injury; hypopituitarism; neuroendocrine dysfunction; hypocortisolism; Addisonian crisis traumatic brain injury; hypopituitarism; neuroendocrine dysfunction; hypocortisolism; Addisonian crisis
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Streetz-van der Werf, C.; Karges, W.; Blaum, M.; Kreitschmann-Andermahr, I. Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism. J. Clin. Med. 2015, 4, 965-969.

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