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Membranes 2016, 6(4), 55; doi:10.3390/membranes6040055

Application of Semipermeable Membranes in Glucose Biosensing

Bioelectronics Laboratory, Department of Computer Science and Electrical Engineering, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA
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Author to whom correspondence should be addressed.
Academic Editor: Hsueh-Chia Chang
Received: 30 October 2016 / Revised: 27 November 2016 / Accepted: 8 December 2016 / Published: 14 December 2016
(This article belongs to the Special Issue Feature Papers)
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Abstract

Glucose biosensors have received significant attention in recent years due to the escalating mortality rate of diabetes mellitus. Although there is currently no cure for diabetes mellitus, individuals living with diabetes can lead a normal life by maintaining tight control of their blood glucose levels using glucose biosensors (e.g., glucometers). Current research in the field is focused on the optimization and improvement in the performance of glucose biosensors by employing a variety of glucose selective enzymes, mediators and semipermeable membranes to improve the electron transfer between the active center of the enzyme and the electrode substrate. Herein, we summarize the different semipermeable membranes used in the fabrication of the glucose biosensor, that result in improved biosensor sensitivity, selectivity, dynamic range, response time and stability. View Full-Text
Keywords: glucose biosensor; semipermeable membrane; glucose oxidase; pyrolloquinoline quinone glucose dehydrogenase; polypyrrole; poly(3,4-ethylenedioxythiophene; cellulose acetate glucose biosensor; semipermeable membrane; glucose oxidase; pyrolloquinoline quinone glucose dehydrogenase; polypyrrole; poly(3,4-ethylenedioxythiophene; cellulose acetate
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Kulkarni, T.; Slaughter, G. Application of Semipermeable Membranes in Glucose Biosensing. Membranes 2016, 6, 55.

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