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Open AccessLetter
Vaccines 2017, 5(4), 43; doi:10.3390/vaccines5040043

A New Whooping Cough Vaccine That May Prevent Colonization and Transmission

1
Aeras, 1405 Research Blvd., Rockville, MD 20850, USA
2
Iliad Biotechnologies, 230 East 15th Street, Suite 1-A, New York, NY 10003, USA
Academic Editor: Toshi Nagata
Received: 8 October 2017 / Revised: 2 November 2017 / Accepted: 6 November 2017 / Published: 10 November 2017
View Full-Text   |   Download PDF [148 KB, uploaded 10 November 2017]

Abstract

This article is a Letter to the Editor. The major purpose of this Letter is to highlight the development of a new genetically altered whooping cough vaccine. Recently a baboon model has been used to show that this next generation pertussis vaccine can prevent colonization, as well as disease, and elicit antibodies against major pertussis antigens. Two phase I clinical trials have been performed, showing that this new vaccine is safe in humans, and a phase II trial will be performed in the US in 2018. View Full-Text
Keywords: Bordetella pertussis; whooping cough vaccine; BPZE1 Bordetella pertussis; whooping cough vaccine; BPZE1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Brennan, M.J. A New Whooping Cough Vaccine That May Prevent Colonization and Transmission. Vaccines 2017, 5, 43.

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