Host Transcriptional Response to Ebola Virus Infection
AbstractEbola virus disease (EVD) is a serious illness that causes severe disease in humans and non-human primates (NHPs) and has mortality rates up to 90%. EVD is caused by the Ebolavirus and currently there are no licensed therapeutics or vaccines to treat EVD. Due to its high mortality rates and potential as a bioterrorist weapon, a better understanding of the disease is of high priority. Multiparametric analysis techniques allow for a more complete understanding of a disease and the host response. Analysis of RNA species present in a sample can lead to a greater understanding of activation or suppression of different states of the immune response. Transcriptomic analyses such as microarrays and RNA-Sequencing (RNA-Seq) have been important tools to better understand the global gene expression response to EVD. In this review, we outline the current knowledge gained by transcriptomic analysis of EVD. View Full-Text
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Speranza, E.; Connor, J.H. Host Transcriptional Response to Ebola Virus Infection. Vaccines 2017, 5, 30.
Speranza E, Connor JH. Host Transcriptional Response to Ebola Virus Infection. Vaccines. 2017; 5(3):30.Chicago/Turabian Style
Speranza, Emily; Connor, John H. 2017. "Host Transcriptional Response to Ebola Virus Infection." Vaccines 5, no. 3: 30.