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Vaccines 2014, 2(1), 107-111; doi:10.3390/vaccines2010107

Meningitis in a School-Aged Child due to Haemophilus influenzae Type E during the Post-Conjugate Vaccine Era—Monroe County, NY, 2011

1
Monroe County Department of Public Health, 111 Westfall Rd., Rochester, NY 14620, USA
2
Department of Pediatrics, University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 690, Rochester, NY 14620, USA
3
Mendon Pediatrics, 30 Assembly Drive, Suite 101 PO Box 488 Mendon, NY 14506, USA
*
Author to whom correspondence should be addressed.
Received: 22 November 2013 / Revised: 30 January 2014 / Accepted: 10 February 2014 / Published: 13 February 2014
View Full-Text   |   Download PDF [271 KB, uploaded 13 February 2014]

Abstract

In late October 2011, the Monroe County Department of Public Health (MCDPH) was notified of a suspected case of meningitis in a 9-year old girl from Monroe County, NY. Laboratory testing at the New York State Department of Health (NYSDOH) Wadsworth Center confirmed the identification of Haemophilus influenzae serotype e (Hie) isolated from the patient’s cerebrospinal fluid (CSF) using real-time polymerase chain reaction (RT-PCR). The universal immunization of infants with conjugate H. influenzae type b (Hib) vaccine has significantly reduced the incidence of invasive Hib disease, including meningitis, one of the most serious complications for infected children. Not surprisingly, as the epidemiology of invasive H. influenzae continues to change, non-Hib serotypes will likely become more common. The findings reported here underscore the importance for clinicians, public health officials, and laboratory staff to consider non-Hib pathogens in pediatric cases of meningitis, especially when initial investigations are inconclusive. View Full-Text
Keywords: Haemophilus influenza; public health; real-time polymerase chain reaction (RT-PCR) Haemophilus influenza; public health; real-time polymerase chain reaction (RT-PCR)
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Kennedy, B.S.; Weimer, A.C.; Bedard, B.; Nayak, J.L.; Sacheli, D.; Ricci, J.; Meyer, D.D.; Hubbard, D. Meningitis in a School-Aged Child due to Haemophilus influenzae Type E during the Post-Conjugate Vaccine Era—Monroe County, NY, 2011. Vaccines 2014, 2, 107-111.

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