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Hepatitis B Vaccination in Pregnancy in the United States
Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA
* Author to whom correspondence should be addressed.
Received: 22 February 2013; in revised form: 16 April 2013 / Accepted: 2 May 2013 / Published: 8 May 2013
Abstract: Hepatitis B remains a significant health issue worldwide, and contributes significantly to the incidence of cirrhosis and hepatocellular carcinoma. Widespread adoption of hepatitis B vaccination strategies has lead to significant declines in acute hepatitis B infections. Current recommendations for vaccination in the non-pregnant population include vaccinating all persons found to have risk-factors for disease acquisition. Hepatitis B virus is known to occur through vertical transmission or early childhood transmission, and strategies to decrease transmission include avoidance of exposure, avoidance of high-risk behaviors, universal screening of women during pregnancy, and active and passive immunization. It is currently recommended that all pregnant women undergo screening for hepatitis B virus at presentation for prenatal care. Those who engage in high-risk behavior should be re-screened at presentation for delivery. Studies have demonstrated the safety and efficacy of the hepatitis B vaccine in pregnancy, and its use is an important component in prevention of disease acquisition. Pregnant women in the United States who are found to be at risk for disease acquisition should be specifically targeted for vaccination.
Keywords: hepatitis B vaccine; immunization; pregnancy
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MDPI and ACS Style
Stewart, R.D.; Sheffield, J.S. Hepatitis B Vaccination in Pregnancy in the United States. Vaccines 2013, 1, 167-173.
Stewart RD, Sheffield JS. Hepatitis B Vaccination in Pregnancy in the United States. Vaccines. 2013; 1(2):167-173.
Stewart, Robert D.; Sheffield, Jeanne S. 2013. "Hepatitis B Vaccination in Pregnancy in the United States." Vaccines 1, no. 2: 167-173.