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From the third issue of 2017, Microarrays has changed its name to High-Throughput.

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Microarrays 2015, 4(4), 551-569; doi:10.3390/microarrays4040551

SNPs Array Karyotyping in Non-Hodgkin Lymphoma

Department of Experimental, Diagnostic, and Specialty Medicine; Hematopathology Unit, S. Orsola-Malpighi Hospital, Bologna 40138, Italy
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Author to whom correspondence should be addressed.
Academic Editor: Jari Louhelainen
Received: 19 August 2015 / Revised: 29 October 2015 / Accepted: 4 November 2015 / Published: 12 November 2015
(This article belongs to the Special Issue SNP Array)
View Full-Text   |   Download PDF [550 KB, uploaded 12 November 2015]

Abstract

The traditional methods for detection of chromosomal aberrations, which included cytogenetic or gene candidate solutions, suffered from low sensitivity or the need for previous knowledge of the target regions of the genome. With the advent of single nucleotide polymorphism (SNP) arrays, genome screening at global level in order to find chromosomal aberrations like copy number variants, DNA amplifications, deletions, and also loss of heterozygosity became feasible. In this review, we present an update of the knowledge, gained by SNPs arrays, of the genomic complexity of the most important subtypes of non-Hodgkin lymphomas. View Full-Text
Keywords: non-Hodgkin lymphoma; single nucleotide polymorphism (SNP) array; genetic aberrations non-Hodgkin lymphoma; single nucleotide polymorphism (SNP) array; genetic aberrations
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Etebari, M.; Navari, M.; Piccaluga, P.P. SNPs Array Karyotyping in Non-Hodgkin Lymphoma. Microarrays 2015, 4, 551-569.

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