Next Article in Journal
Reducing Fall Risk with Combined Motor and Cognitive Training in Elderly Fallers
Next Article in Special Issue
A Neurophysiological Perspective on a Preventive Treatment against Schizophrenia Using Transcranial Electric Stimulation of the Corticothalamic Pathway
Previous Article in Journal
Spatial Impairment and Memory in Genetic Disorders: Insights from Mouse Models
Previous Article in Special Issue
Single Electrode Deep Brain Stimulation with Dual Targeting at Dual Frequency for the Treatment of Chronic Pain: A Case Series and Review of the Literature
Article Menu

Export Article

Open AccessReview
Brain Sci. 2017, 7(2), 18; doi:10.3390/brainsci7020018

Surgical Neurostimulation for Spinal Cord Injury

1
Academic Neurosurgery Unit, St George’s, University of London, London SW17 0RE, UK
2
Division of Brain Sciences, Faculty of Medicine, Imperial College London, London W6 8RF, UK
3
The Miami Project to Cure Paralysis and Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
*
Author to whom correspondence should be addressed.
Academic Editors: Tipu Aziz and Alex Green
Received: 21 December 2016 / Revised: 30 January 2017 / Accepted: 2 February 2017 / Published: 10 February 2017
(This article belongs to the Special Issue Deep Brain Stimulation (DBS) Applications)
View Full-Text   |   Download PDF [550 KB, uploaded 10 February 2017]   |  

Abstract

Traumatic spinal cord injury (SCI) is a devastating neurological condition characterized by a constellation of symptoms including paralysis, paraesthesia, pain, cardiovascular, bladder, bowel and sexual dysfunction. Current treatment for SCI involves acute resuscitation, aggressive rehabilitation and symptomatic treatment for complications. Despite the progress in scientific understanding, regenerative therapies are lacking. In this review, we outline the current state and future potential of invasive and non-invasive neuromodulation strategies including deep brain stimulation (DBS), spinal cord stimulation (SCS), motor cortex stimulation (MCS), transcutaneous direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS) in the context of SCI. We consider the ability of these therapies to address pain, sensorimotor symptoms and autonomic dysregulation associated with SCI. In addition to the potential to make important contributions to SCI treatment, neuromodulation has the added ability to contribute to our understanding of spinal cord neurobiology and the pathophysiology of SCI. View Full-Text
Keywords: spinal cord injury; spinal cord stimulation; deep brain stimulation; neuromodulation spinal cord injury; spinal cord stimulation; deep brain stimulation; neuromodulation
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chari, A.; Hentall, I.D.; Papadopoulos, M.C.; Pereira, E.A.C. Surgical Neurostimulation for Spinal Cord Injury. Brain Sci. 2017, 7, 18.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Brain Sci. EISSN 2076-3425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top