Next Article in Journal
Base Pounding Model and Response Analysis of Base-Isolated Structures under Earthquake Excitation
Previous Article in Journal
A Multi-Source Early Warning System of MEMS Based Wireless Monitoring for Rainfall-Induced Landslides
Article Menu

Export Article

Open AccessArticle
Appl. Sci. 2017, 7(12), 1235; doi:10.3390/app7121235

Time-Domain Functional Diffuse Optical Tomography System Based on Fiber-Free Silicon Photomultipliers

1
Consiglio Nazionale delle Ricerche, Istituto di Fotonica e Nanotecnologie, Piazza Leonardo da Vinci 32, 20133 Milano, Italy
2
ICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, Av. Carl Friedrich Gauss, 3, 08860 Barcelona, Spain
3
Politecnico di Milano, Dipartimento di Fisica, Piazza Leonardo da Vinci 32, 20133 Milano, Italy
4
Institució Catalana de Recerca i Estudis Avançats (ICREA), Passeig de Lluís Companys, 23, 08015 Barcelona, Spain
5
Department of Computer Science, University College London, Gower Street, London WC1E 6BT, UK
6
Dipartimento di Fisica e Astronomia dell’Università degli Studi di Firenze, Via G. Sansone 1, Sesto Fiorentino, 50019 Firenze, Italy
*
Author to whom correspondence should be addressed.
Received: 2 October 2017 / Revised: 2 November 2017 / Accepted: 24 November 2017 / Published: 29 November 2017
(This article belongs to the Section Optics and Lasers)
View Full-Text   |   Download PDF [5489 KB, uploaded 29 November 2017]   |  

Abstract

Based on recent developments in both single-photon detectors and timing electronic circuits, we designed a compact and cost effective time-domain diffuse optical tomography system operated at 1 Hz acquisition rate, based on eight silicon photomultipliers and an 8-channel time-to-digital converter. The compact detectors are directly hosted on the probe in a circular arrangement around a single light injection fiber, so to maximize light harvesting. Tomography is achieved exploiting the depth sensitivity that is encoded in the arrival time of detected photons. The system performances were evaluated on simulations to assess possible the limitations arising from the use of a single injection point, and then on phantoms and in vivo to prove the eligibility of these technologies for diffuse optical tomography. View Full-Text
Keywords: functional imaging; diffuse optical tomography; time-correlated single-photon counting; silicon photomultipliers functional imaging; diffuse optical tomography; time-correlated single-photon counting; silicon photomultipliers
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Farina, A.; Tagliabue, S.; Di Sieno, L.; Martinenghi, E.; Durduran, T.; Arridge, S.; Martelli, F.; Torricelli, A.; Pifferi, A.; Dalla Mora, A. Time-Domain Functional Diffuse Optical Tomography System Based on Fiber-Free Silicon Photomultipliers. Appl. Sci. 2017, 7, 1235.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Appl. Sci. EISSN 2076-3417 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top