Alum as a Catalyst for the Synthesis of Bispyrazole Derivatives
AbstractCompounds with pyrazolemoieties as nitrogen-containing heterocyclic systems have received attention owing to their diverse biological activities. Alum (KAl(SO4)2∙12H2O) is an inexpensive, reusable and nontoxic catalyst used to synthesize 1H-pyrazole derivatives via the reaction of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one and carbonyl compound under solvent-free conditions at 60 °C. The proposed method has been used for the preparation of 1H-pyrazole derivatives to yield green products for cleaning-in-place and to avoid toxic catalysts and hazardous solvents in accordance with the philosophy of sustainable chemistry. View Full-Text
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Zolfigol, M.A.; Khazaei, A.; Karimitabar, F.; Hamidi, M. Alum as a Catalyst for the Synthesis of Bispyrazole Derivatives. Appl. Sci. 2016, 6, 27.
Zolfigol MA, Khazaei A, Karimitabar F, Hamidi M. Alum as a Catalyst for the Synthesis of Bispyrazole Derivatives. Applied Sciences. 2016; 6(1):27.Chicago/Turabian Style
Zolfigol, Mohammad A.; Khazaei, Ardeshir; Karimitabar, Fatemeh; Hamidi, Masoud. 2016. "Alum as a Catalyst for the Synthesis of Bispyrazole Derivatives." Appl. Sci. 6, no. 1: 27.
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