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Med. Sci. 2018, 6(1), 1; doi:10.3390/medsci6010001

Carbapenem Resistance: A Review

1
Department of Medical Laboratory Sciences (Microbiology Division), School of Biomedical & Allied Health Sciences, College of Health Sciences, University of Ghana, Korle Bu KB 143 Accra, Ghana
2
Biomolecular Science Research Centre, Sheffield Hallam University, Sheffield S1 1WB, UK
3
Department of Medical Microbiology, School of Biomedical & Allied Health Sciences, College of Health Sciences, University of Ghana, Korle Bu KB 143 Accra, Ghana
*
Author to whom correspondence should be addressed.
Received: 6 November 2017 / Revised: 25 November 2017 / Accepted: 5 December 2017 / Published: 21 December 2017
(This article belongs to the Section Immunology and Infectious Diseases)
View Full-Text   |   Download PDF [331 KB, uploaded 21 December 2017]

Abstract

Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject. View Full-Text
Keywords: Gram negative bacilli; carbapenems; antibiotic resistance; carbapenemases Gram negative bacilli; carbapenems; antibiotic resistance; carbapenemases
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Codjoe, F.S.; Donkor, E.S. Carbapenem Resistance: A Review. Med. Sci. 2018, 6, 1.

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