Next Article in Journal
Assessment and Screening of the Risk Factors in Metabolic Syndrome
Previous Article in Journal
Application of Massively Parallel Sequencing in the Clinical Diagnostic Testing of Inherited Cardiac Conditions
Article Menu

Export Article

Open AccessArticle
Med. Sci. 2014, 2(3), 127-139; doi:10.3390/medsci2030127

Pattern Recognition of Gene Expression with Singular Spectrum Analysis

The Staistical Research Centre, Bournemouth University, Bournemouth BH8 8EB, UK
*
Author to whom correspondence should be addressed.
Received: 20 February 2014 / Revised: 3 May 2014 / Accepted: 22 May 2014 / Published: 1 July 2014
View Full-Text   |   Download PDF [603 KB, uploaded 2 July 2014]   |  

Abstract

Drosophila segmentation as a model organism is one of the most highly studied. Among many maternal segmentation coordinate genes, bicoid protein pattern plays a significant role during Drosophila embryogenesis, since this gradient determines most aspects of head and thorax development. Despite the fact that several models have been proposed to describe the bicoid gradient, due to its association with considerable error, each can only partially explain bicoid characteristics. In this paper, a modified version of singular spectrum analysis is examined for filtering and extracting the bicoid gene expression signal. The results with strong evidence indicate that the proposed technique is able to remove noise more effectively and can be considered as a promising method for filtering gene expression measurements for other applications. View Full-Text
Keywords: Drosophila melanogaster; segmentation; signal extraction; singular spectrum analysis Drosophila melanogaster; segmentation; signal extraction; singular spectrum analysis
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Hassani, H.; Ghodsi, Z. Pattern Recognition of Gene Expression with Singular Spectrum Analysis. Med. Sci. 2014, 2, 127-139.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Med. Sci. EISSN 2076-3271 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top