Next Article in Journal
On-FarmWelfare Assessment Protocol for Adult Dairy Goats in Intensive Production Systems
Next Article in Special Issue
Metabolic Disorders in the Transition Period Indicate that the Dairy Cows’ Ability to Adapt is Overstressed
Previous Article in Journal
Workplace Injuries in Thoroughbred Racing: An Analysis of Insurance Payments and Injuries amongst Jockeys in Australia from 2002 to 2010
Previous Article in Special Issue
Evidence for a Role of Prolactin in Mediating Effects of Photoperiod during the Dry Period
Article Menu

Export Article

Open AccessArticle
Animals 2015, 5(3), 910-933; doi:10.3390/ani5030391

Effects of Prepartum Dietary Energy Level and Nicotinic Acid Supplementation on Immunological, Hematological and Biochemical Parameters of Periparturient Dairy Cows Differing in Parity

1
Institute of Animal Nutrition, Friedrich-Loeffler-Insitute (FLI), Federal Research Institute for Animal Health, Bundesallee 50, 38116 Brunswick, Germany
2
Department of Physiology, University of Veterinary Medicine Hanover, Bischofsholer Damm 15, 30173 Hanover, Germany
3
Clinic for Cattle, University of Veterinary Medicine Hanover, Bischofsholer Damm 15, 30173 Hanover, Germany
Present address: Institute of Animal Nutrition, University of Hohenheim, 70599 Stuttgart, Germany;
*
Author to whom correspondence should be addressed.
Academic Editor: Clive Phillips
Received: 30 April 2015 / Revised: 13 August 2015 / Accepted: 31 August 2015 / Published: 8 September 2015
(This article belongs to the Special Issue Nutritional and Metabolic Health of Dairy Cow)
View Full-Text   |   Download PDF [360 KB, uploaded 8 September 2015]   |  

Simple Summary

Several biological changes occur during the transition from late pregnancy to early lactation which is associated with a high susceptibility of health disorders. Nicotinic acid, as feed additive, is suggested to balance catabolic metabolism of periparturient dairy cows by attenuating lipolysis and impact production performance. This study provides information of the biological changes occurring around parturition with special emphasis on differences between primiparous and multiparous cows. Present results showed that energy-dense feeding prepartum did not result in metabolic imbalances postpartum in dairy cows which were similar in body condition score. Nicotinic acid supplementation did not reveal any effect.

Abstract

The periparturient period is critical according to health, productivity and profitability. As this period is fundamental for the success of the lactation period, the interest in improving periparturient health by dietary supplements increased in recent years. The present study investigated the effects of feeding nicotinic acid (NA) combined with varying dietary energy densities on immunological, hematological and biochemical parameters of periparturient cows differing in parity. Thirty-six multiparous and 20 primiparous dairy cows were enrolled in the study 42 days before expected parturition date until 100 days postpartum with the half of the cows being supplemented with 24 g of NA/d. After parturition a diet with 30% concentrate was fed to all cows which was followed by different concentrate escalation strategies. Dietary NA supplementation was ceased on day 24 postpartum. Dietary NA increased (P = 0.010) serum nicotinamide concentrations (mean of 3.35 ± 1.65 µg/mL), whereas NA could not be detected. Present data emphasize that periparturient cows are faced with major physiological challenges and that both parity-groups have different prerequisites to adapt to those changes irrespective of NA supplementation. The overfeeding of energy to cows which were similar in body condition score had only minor effects on periparturient immune system function and the metabolism of those cows. View Full-Text
Keywords: periparturient; niacin; dairy cow; immune system; PBMC; CD4; CD8 periparturient; niacin; dairy cow; immune system; PBMC; CD4; CD8
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Tienken, R.; Kersten, S.; Frahm, J.; Hüther, L.; Meyer, U.; Huber, K.; Rehage, J.; Dänicke, S. Effects of Prepartum Dietary Energy Level and Nicotinic Acid Supplementation on Immunological, Hematological and Biochemical Parameters of Periparturient Dairy Cows Differing in Parity. Animals 2015, 5, 910-933.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Animals EISSN 2076-2615 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top