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Pathogens 2018, 7(3), 72; https://doi.org/10.3390/pathogens7030072

Miliary Tuberculosis Presenting with Hyponatremia and ARDS in an 82-Year-Old Immunocompetent Female

1
Department of Internal Medicine, Hospital Universitario Fundación Alcorcón, 28922 Madrid, Spain
2
School of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain
3
Department of Nuclear Medicine, Hospital Puerta de Hierro, 28222 Madrid, Spain
4
Department of Pathology, Hospital Universitario Fundación Alcorcón, 28922 Madrid, Spain
*
Author to whom correspondence should be addressed.
Received: 5 July 2018 / Revised: 28 August 2018 / Accepted: 28 August 2018 / Published: 5 September 2018
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Abstract

An immunocompetent 82-year-old female was admitted to our hospital due to fever without clear origin and hyponatremia. In the following days, an acute and bilateral pulmonary infiltrate appeared with a progressive worsening in respiratory function. Chest x-ray and CT (Computed tomography) showed bilateral reticulonodular infiltrates. Bronchoscopic aspiration and bronchoalveolar lavage (BAL), and transbronchial lung biopsy (TBBX) studies did not reveal microbiological and histopathological diagnosis. Broad-spectrum antibiotics were non-effective, and the patient died due to respiratory failure. Necropsy study revealed a miliary tuberculosis affecting lungs, liver, bone marrow, spleen, kidney, arteries, pancreas, and adrenal glands. Some weeks after the patient´s death, mycobacterial cultures from sputum, BAL and TBBX samples were positive for Mycobacterium tuberculosis. View Full-Text
Keywords: miliary tuberculosis; acute respiratory distress syndrome (ARDS); hyponatremia; necropsy miliary tuberculosis; acute respiratory distress syndrome (ARDS); hyponatremia; necropsy
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MDPI and ACS Style

Herreros, B.; Plaza, I.; García, R.; Chichón, M.; Guerrero, C.; Pintor, E. Miliary Tuberculosis Presenting with Hyponatremia and ARDS in an 82-Year-Old Immunocompetent Female. Pathogens 2018, 7, 72.

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