Next Article in Journal / Special Issue
Biomimickry of UPEC Cytoinvasion: A Novel Concept for Improved Drug Delivery in UTI
Previous Article in Journal
Importance of B Lymphocytes and the IgG-Binding Protein Sbi in Staphylococcus aureus Skin Infection
Previous Article in Special Issue
Novel Strategies in the Prevention and Treatment of Urinary Tract Infections
Article Menu

Export Article

Open AccessReview
Pathogens 2016, 5(1), 14; doi:10.3390/pathogens5010014

Genetic Variations in Vesicoureteral Reflux Sequelae

1
Innate Immunity Translational Research Center, Children’s Foundation Research Institute, Le Bonheur Children’s Hospital, Memphis, TN 38103, USA
2
Department of Pediatrics, Nationwide Children’s Hospital, Columbus, OH 43205, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Catharina Svanborg
Received: 11 September 2015 / Revised: 20 January 2016 / Accepted: 21 January 2016 / Published: 2 February 2016
(This article belongs to the Special Issue Molecular Aspects of Urinary Tract Infection)
View Full-Text   |   Download PDF [498 KB, uploaded 2 February 2016]   |  

Abstract

Urinary tract infections (UTI) are a common condition in children. Vesicoureteral reflux (VUR) represents a common associated condition with childhood UTI. UTI susceptibility appears to have a genetic component based on family and UTI cohort studies. Targeted analysis of innate immune system genetic variations indicate that these variations are important in UTI susceptibility. In this overview, we discuss how current cohorts and genetic strategies can be implemented to discover new susceptibility loci in patients with UTI. View Full-Text
Keywords: vesicoureteral reflux; genetics; copy number variations; urinary tract infections vesicoureteral reflux; genetics; copy number variations; urinary tract infections
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Hains, D.S.; Schwaderer, A.L. Genetic Variations in Vesicoureteral Reflux Sequelae. Pathogens 2016, 5, 14.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Pathogens EISSN 2076-0817 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top