Next Article in Journal
Frequent Insect Visitors Are Not Always Pollen Carriers in Hybrid Carrot Pollination
Previous Article in Journal
Host-Specific Activation of Entomopathogenic Nematode Infective Juveniles
Previous Article in Special Issue
Tri-Trophic Impacts of Bt-Transgenic Maize on Parasitoid Size and Fluctuating Asymmetry in Native vs. Novel Host-Parasitoid Interactions in East Africa
Article Menu

Export Article

Open AccessArticle
Insects 2018, 9(2), 60; https://doi.org/10.3390/insects9020060

Effect of the Topical Repellent para-Menthane-3,8-diol on Blood Feeding Behavior and Fecundity of the Dengue Virus Vector Aedes aegypti

1
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
2
Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN 46556, USA
3
Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN 46556, USA
*
Author to whom correspondence should be addressed.
Received: 13 April 2018 / Revised: 23 May 2018 / Accepted: 25 May 2018 / Published: 4 June 2018
(This article belongs to the Special Issue Integrated Pest Management)
Full-Text   |   PDF [1923 KB, uploaded 4 June 2018]   |  

Abstract

Dengue fever is an acute disease caused by the dengue virus and transmitted primarily by the mosquito Aedes aegypti. The current strategy for dengue prevention is vector control including the use of topical repellents to reduce mosquito biting. Although N,N-diethyl-m-methylbenzamide (DEET) is the most common active ingredient in topical repellent products, para-menthane-3,8-diol (PMD) is also used commercially. Studies have indicated PMD reduced biting by 90–95% for up to 6–8 h, similar to the efficacy of DEET, depending on the testing environment. The purpose of this study was to evaluate the behavioral effects of PMD on Ae. aegypti blood feeding and fecundity to explore the potential impact of PMD on downstream mosquito life-history traits. Two experiments were performed. In both experiments, cohorts of female Ae. aegypti (Belize strain) were exposed to 20% PMD or ethanol for 10 min in a closed system and introduced to an artificial membrane feeding system. Following a 30min feed time, mosquitoes of Experiment 1 were killed and weighed as a proxy measure of blood meal, whereas mosquitoes of Experiment 2 were monitored for oviposition, a measure of fecundity. Results showed a statistically significant reduction (p < 0.001) in the percentage of Ae. aegypti that blood-fed when exposed to PMD (38%) compared to those non-exposed (49%). No significant difference in fecundity between test populations was indicated. These findings suggest that exposure of Ae. aegypti to 20% PMD may influence the probability of subsequent blood feeding but of those mosquitoes that do blood feed, egg-lay density is not affected. Further studies are warranted to investigate the full range of effects of PMD exposure on other Ae. aegypti life-history traits such as mating, to continue characterizing the potential effects of PMD to impact overall vector population dynamics. View Full-Text
Keywords: Aedes aegypti; repellent; para-menthane-3,8-diol; PMD; blood feeding; fecundity Aedes aegypti; repellent; para-menthane-3,8-diol; PMD; blood feeding; fecundity
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Lee, J.; Choi, D.B.; Liu, F.; Grieco, J.P.; Achee, N.L. Effect of the Topical Repellent para-Menthane-3,8-diol on Blood Feeding Behavior and Fecundity of the Dengue Virus Vector Aedes aegypti. Insects 2018, 9, 60.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Insects EISSN 2075-4450 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top