Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment
AbstractNeutrophil extracellular traps (NETs) are a network of extracellular fibers, compounds of chromatin, neutrophil DNA and histones, which are covered with antimicrobial enzymes with granular components. Autophagy and the production of reactive oxygen species (ROS) by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase are essential in the formation of NETs. There is increasing evidence that suggests that autoantibodies against beta-2-glycoprotein-1 (B2GP1) induce NETs and enhance thrombosis. Past research on new mechanisms of thrombosis formation in antiphospholipid syndrome (APS) has elucidated the pharmacokinetics of the most common medication in the treatment of the disease. View Full-Text
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Bravo-Barrera, J.; Kourilovitch, M.; Galarza-Maldonado, C. Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment. Antibodies 2017, 6, 4.
Bravo-Barrera J, Kourilovitch M, Galarza-Maldonado C. Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment. Antibodies. 2017; 6(1):4.Chicago/Turabian Style
Bravo-Barrera, Jessica; Kourilovitch, Maria; Galarza-Maldonado, Claudio. 2017. "Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment." Antibodies 6, no. 1: 4.
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