Telomerase Activation in Hematological Malignancies
AbstractTelomerase expression and telomere maintenance are critical for cell proliferation and survival, and they play important roles in development and cancer, including hematological malignancies. Transcriptional regulation of the rate-limiting subunit of human telomerase reverse transcriptase gen (hTERT) is a complex process, and unveiling the mechanisms behind its reactivation is an important step for the development of diagnostic and therapeutic applications. Here, we review the main mechanisms of telomerase activation and the associated hematologic malignancies. View Full-Text
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Ropio, J.; Merlio, J.-P.; Soares, P.; Chevret, E. Telomerase Activation in Hematological Malignancies. Genes 2016, 7, 61.
Ropio J, Merlio J-P, Soares P, Chevret E. Telomerase Activation in Hematological Malignancies. Genes. 2016; 7(9):61.Chicago/Turabian Style
Ropio, Joana; Merlio, Jean-Philippe; Soares, Paula; Chevret, Edith. 2016. "Telomerase Activation in Hematological Malignancies." Genes 7, no. 9: 61.
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