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Genes 2015, 6(4), 957-976; doi:10.3390/genes6040957

Impact of Chromatin on HIV Replication

1
Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
2
Graduate Program in Microbiology, Boston University School of Medicine, Boston, MA 02118, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Jessica Tyler
Received: 13 August 2015 / Revised: 14 September 2015 / Accepted: 22 September 2015 / Published: 30 September 2015
(This article belongs to the Special Issue Chromatin Dynamics)
View Full-Text   |   Download PDF [701 KB, uploaded 30 September 2015]   |  

Abstract

Chromatin influences Human Immunodeficiency Virus (HIV) integration and replication. This review highlights critical host factors that influence chromatin structure and organization and that also impact HIV integration, transcriptional regulation and latency. Furthermore, recent attempts to target chromatin associated factors to reduce the HIV proviral load are discussed. View Full-Text
Keywords: HIV; chromatin; integration; transcription; latency HIV; chromatin; integration; transcription; latency
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Agosto, L.M.; Gagne, M.; Henderson, A.J. Impact of Chromatin on HIV Replication. Genes 2015, 6, 957-976.

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