Next Article in Journal
Next Article in Special Issue
Previous Article in Journal
Previous Article in Special Issue
Genes 2011, 2(2), 313-331; doi:10.3390/genes2020313
Article

The Rate and Tract Length of Gene Conversion between Duplicated Genes

1
, 1
 and 1,2,*
Received: 17 February 2011; in revised form: 11 March 2011 / Accepted: 17 March 2011 / Published: 25 March 2011
(This article belongs to the Special Issue Gene Conversion in Duplicated Genes)
View Full-Text   |   Download PDF [642 KB, uploaded 25 March 2011]
Abstract: Interlocus gene conversion occurs such that a certain length of DNA fragment is non-reciprocally transferred (copied and pasted) between paralogous regions. To understand the rate and tract length of gene conversion, there are two major approaches. One is based on mutation-accumulation experiments, and the other uses natural DNA sequence variation. In this review, we overview the two major approaches and discuss their advantages and disadvantages. In addition, to demonstrate the importance of statistical analysis of empirical and evolutionary data for estimating tract length, we apply a maximum likelihood method to several data sets.
Keywords: interlocus gene conversion; tract length; gene conversion rate interlocus gene conversion; tract length; gene conversion rate
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Mansai, S.P.; Kado, T.; Innan, H. The Rate and Tract Length of Gene Conversion between Duplicated Genes. Genes 2011, 2, 313-331.

AMA Style

Mansai SP, Kado T, Innan H. The Rate and Tract Length of Gene Conversion between Duplicated Genes. Genes. 2011; 2(2):313-331.

Chicago/Turabian Style

Mansai, Sayaka P.; Kado, Tomoyuki; Innan, Hideki. 2011. "The Rate and Tract Length of Gene Conversion between Duplicated Genes." Genes 2, no. 2: 313-331.


Genes EISSN 2073-4425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert