P-value color scale
> 10-3 10-3 to 10-5 10-5 to 10-7 10-7 to 10-9 < 10-9

 

GO term Description P-value FDR q-value Enrichment (N, B, n, b) Genes
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 7.36E-19 1.02E-14 3.49 (10334,85,1776,51) [+] Show genes
GO:0006613 cotranslational protein targeting to membrane 2.29E-17 1.59E-13 3.30 (10334,90,1776,51) [+] Show genes
GO:0006412 translation 1.38E-16 6.4E-13 2.53 (10334,177,1776,77) [+] Show genes
GO:0045047 protein targeting to ER 1.51E-15 5.25E-12 3.03 (10334,100,1776,52) [+] Show genes
GO:0043043 peptide biosynthetic process 2.55E-15 7.09E-12 2.39 (10334,192,1776,79) [+] Show genes
GO:0070972 protein localization to endoplasmic reticulum 3.22E-15 7.48E-12 2.86 (10334,114,1776,56) [+] Show genes
GO:0072599 establishment of protein localization to endoplasmic reticulum 7.47E-15 1.48E-11 2.94 (10334,103,1776,52) [+] Show genes
GO:0006413 translational initiation 8.05E-15 1.4E-11 2.71 (10334,129,1776,60) [+] Show genes
GO:0019083 viral transcription 1.15E-14 1.77E-11 2.88 (10334,107,1776,53) [+] Show genes
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 7.89E-14 1.1E-10 2.78 (10334,111,1776,53) [+] Show genes
GO:0006091 generation of precursor metabolites and energy 1.52E-13 1.92E-10 2.02 (10334,294,1776,102) [+] Show genes
GO:0043604 amide biosynthetic process 2.51E-13 2.91E-10 2.03 (10334,284,1776,99) [+] Show genes
GO:1901566 organonitrogen compound biosynthetic process 1.16E-11 1.24E-8 1.55 (10334,738,1776,197) [+] Show genes
GO:0006518 peptide metabolic process 1.2E-11 1.2E-8 1.95 (10334,280,1776,94) [+] Show genes
GO:0043603 cellular amide metabolic process 1.95E-11 1.81E-8 1.70 (10334,471,1776,138) [+] Show genes
GO:0044281 small molecule metabolic process 5.64E-11 4.91E-8 1.39 (10334,1275,1776,304) [+] Show genes
GO:0006612 protein targeting to membrane 8.1E-11 6.63E-8 2.34 (10334,139,1776,56) [+] Show genes
GO:0022900 electron transport chain 1.13E-10 8.72E-8 2.33 (10334,140,1776,56) [+] Show genes
GO:0022904 respiratory electron transport chain 1.19E-10 8.75E-8 2.69 (10334,91,1776,42) [+] Show genes
GO:0055114 oxidation-reduction process 2.95E-10 2.05E-7 1.55 (10334,645,1776,172) [+] Show genes
GO:0017144 drug metabolic process 1.27E-8 8.39E-6 1.63 (10334,413,1776,116) [+] Show genes
GO:0019752 carboxylic acid metabolic process 4.49E-8 2.84E-5 1.47 (10334,653,1776,165) [+] Show genes
GO:0090150 establishment of protein localization to membrane 5.24E-8 3.17E-5 1.87 (10334,215,1776,69) [+] Show genes
GO:0072594 establishment of protein localization to organelle 1.22E-7 7.09E-5 1.65 (10334,342,1776,97) [+] Show genes
GO:0000956 nuclear-transcribed mRNA catabolic process 2.14E-7 1.19E-4 1.91 (10334,180,1776,59) [+] Show genes
GO:0055086 nucleobase-containing small molecule metabolic process 5.96E-7 3.19E-4 1.52 (10334,460,1776,120) [+] Show genes
GO:0006753 nucleoside phosphate metabolic process 5.96E-7 3.07E-4 1.56 (10334,399,1776,107) [+] Show genes
GO:0006099 tricarboxylic acid cycle 6.44E-7 3.2E-4 3.27 (10334,32,1776,18) [+] Show genes
GO:0033108 mitochondrial respiratory chain complex assembly 7.04E-7 3.38E-4 2.30 (10334,86,1776,34) [+] Show genes
GO:0043436 oxoacid metabolic process 7.91E-7 3.67E-4 1.40 (10334,710,1776,171) [+] Show genes
GO:0009117 nucleotide metabolic process 8.08E-7 3.63E-4 1.56 (10334,392,1776,105) [+] Show genes
GO:0006082 organic acid metabolic process 8.77E-7 3.81E-4 1.40 (10334,721,1776,173) [+] Show genes
GO:0072521 purine-containing compound metabolic process 1.11E-6 4.69E-4 1.62 (10334,316,1776,88) [+] Show genes
GO:0002181 cytoplasmic translation 1.12E-6 4.58E-4 2.98 (10334,39,1776,20) [+] Show genes
GO:0006101 citrate metabolic process 1.19E-6 4.73E-4 3.17 (10334,33,1776,18) [+] Show genes
GO:0006402 mRNA catabolic process 1.28E-6 4.96E-4 1.81 (10334,193,1776,60) [+] Show genes
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 1.52E-6 5.7E-4 2.78 (10334,46,1776,22) [+] Show genes
GO:0010257 NADH dehydrogenase complex assembly 1.85E-6 6.78E-4 2.52 (10334,60,1776,26) [+] Show genes
GO:0032981 mitochondrial respiratory chain complex I assembly 1.85E-6 6.6E-4 2.52 (10334,60,1776,26) [+] Show genes
GO:0034655 nucleobase-containing compound catabolic process 2.33E-6 8.12E-4 1.58 (10334,335,1776,91) [+] Show genes
GO:0006605 protein targeting 3.03E-6 1.03E-3 1.62 (10334,291,1776,81) [+] Show genes
GO:0006163 purine nucleotide metabolic process 4.04E-6 1.34E-3 1.61 (10334,293,1776,81) [+] Show genes
GO:0046700 heterocycle catabolic process 4.35E-6 1.41E-3 1.54 (10334,363,1776,96) [+] Show genes
GO:1901361 organic cyclic compound catabolic process 4.93E-6 1.56E-3 1.51 (10334,397,1776,103) [+] Show genes
GO:0009150 purine ribonucleotide metabolic process 6.05E-6 1.87E-3 1.62 (10334,273,1776,76) [+] Show genes
GO:0072350 tricarboxylic acid metabolic process 6.16E-6 1.86E-3 2.91 (10334,36,1776,18) [+] Show genes
GO:0044270 cellular nitrogen compound catabolic process 6.34E-6 1.88E-3 1.53 (10334,366,1776,96) [+] Show genes
GO:1901576 organic substance biosynthetic process 7.74E-6 2.24E-3 1.21 (10334,1779,1776,370) [+] Show genes
GO:0072657 protein localization to membrane 1.13E-5 3.21E-3 1.50 (10334,385,1776,99) [+] Show genes
GO:0019693 ribose phosphate metabolic process 1.22E-5 3.39E-3 1.57 (10334,301,1776,81) [+] Show genes
GO:0019439 aromatic compound catabolic process 1.35E-5 3.68E-3 1.50 (10334,377,1776,97) [+] Show genes
GO:0009058 biosynthetic process 1.45E-5 3.87E-3 1.20 (10334,1812,1776,374) [+] Show genes
GO:0006401 RNA catabolic process 1.65E-5 4.34E-3 1.67 (10334,212,1776,61) [+] Show genes
GO:0009259 ribonucleotide metabolic process 1.71E-5 4.4E-3 1.57 (10334,285,1776,77) [+] Show genes
GO:0032787 monocarboxylic acid metabolic process 2.16E-5 5.46E-3 1.49 (10334,362,1776,93) [+] Show genes
GO:0006732 coenzyme metabolic process 2.19E-5 5.43E-3 1.61 (10334,250,1776,69) [+] Show genes
GO:0006733 oxidoreduction coenzyme metabolic process 3.33E-5 8.12E-3 1.98 (10334,100,1776,34) [+] Show genes
GO:0044249 cellular biosynthetic process 4.02E-5 9.63E-3 1.20 (10334,1696,1776,349) [+] Show genes
GO:0044283 small molecule biosynthetic process 4.88E-5 1.15E-2 1.42 (10334,442,1776,108) [+] Show genes
GO:0098662 inorganic cation transmembrane transport 5.45E-5 1.26E-2 1.52 (10334,294,1776,77) [+] Show genes
GO:0016999 antibiotic metabolic process 7.05E-5 1.61E-2 2.01 (10334,87,1776,30) [+] Show genes
GO:0051704 multi-organism process 7.54E-5 1.69E-2 1.26 (10334,982,1776,213) [+] Show genes
GO:0030316 osteoclast differentiation 7.55E-5 1.67E-2 3.17 (10334,22,1776,12) [+] Show genes

Species used: Homo sapiens

The system has recognized 12276 genes out of 13663 gene terms entered by the user.
12276 genes were recognized by gene symbol and 0 genes by other gene IDs .
1847 duplicate genes were removed (keeping the highest ranking instance of each gene) leaving a total of 10429 genes.
Only 10334 of these genes are associated with a GO term.

The GOrilla database is periodically updated using the GO database and other sources.
The GOrilla database was last updated on Aug 29, 2020

This results page will be available on this site for one month from now (until Oct 1, 2020 ). You can bookmark this page and come back to it later.


'P-value' is the enrichment p-value computed according to the mHG or HG model. This p-value is not corrected for multiple testing of 13915 GO terms.

'FDR q-value' is the correction of the above p-value for multiple testing using the Benjamini and Hochberg (1995) method.
Namely, for the ith term (ranked according to p-value) the FDR q-value is (p-value * number of GO terms) / i.

Enrichment (N, B, n, b) is defined as follows:
N - is the total number of genes
B - is the total number of genes associated with a specific GO term
n - is the number of genes in the top of the user's input list or in the target set when appropriate
b - is the number of genes in the intersection
Enrichment = (b/n) / (B/N)

Genes: For each GO term you can see the list of associated genes that appear in the optimal top of the list.
Each gene name is specified by gene symbol followed by a short description of the gene

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