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Genes 2010, 1(3), 349-356; doi:10.3390/genes1030349
Review

Gene Conversion and Evolution of Gene Families: An Overview

National Institute of Genetics, Mishima, 411-8540, Japan
Received: 16 August 2010 / Revised: 27 September 2010 / Accepted: 28 September 2010 / Published: 30 September 2010
(This article belongs to the Special Issue Gene Conversion in Duplicated Genes)
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Abstract

The importance of gene conversion for the evolution of gene families is reviewed. Four problems concerning gene conversion, i.e., concerted evolution, generation of useful variation, deleterious effects, and relation to neofunctionalization, are discussed by surveying reported examples of evolving gene families. Emphasis is given toward understanding interactive effects of gene conversion and natural selection.
Keywords: interaction of gene conversion and selection; concerted evolution; generation of gene diversity interaction of gene conversion and selection; concerted evolution; generation of gene diversity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ohta, T. Gene Conversion and Evolution of Gene Families: An Overview. Genes 2010, 1, 349-356.

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